Cochlear implants international · 2025
Cochlear device explantation in patients with nasopharyngeal cancer irradiation.
СтатьяМногоцентровое исследованиеНазвание и аннотация: Перевод пока не подготовлен
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Chang Wai Tsz, Ng Iris H Y, Chen Xiaoxin, Lee William T W, Chu T C, Lau Alan T L, Wong Birgitta Y H, Cheng Horace, Lui Kary C M, Tong Michael C F
Аннотация
OBJECTIVES: Cochlear implantation (CI) is feasible for hearing rehabilitation in post-irradiated patients with profound sensorineural hearing loss. Complication especially explantation in patient with history of irradiation is a concern. The study aimed to investigate the incidence and cause of cochlear device explantation in between nasopharyngeal cancer (NPC)-related irradiation when compare with adults without.
METHODS: This was a retrospective multicentre case-control study, which conducted on adults who underwent CI between 1994 and 2024. The rate, reasons and time after implantation of cochlear device explantation, and reimplantation rate were compared.
RESULTS: A total of 1067 ears (122 ears of NPC and 945 ears of non-NPC) were included in the study. The explantation rate was significantly higher in NPC group with a percentage of 7.38% compared with 2.01% in non-NPC group (p < 0.001, OR = 3.908). There was no significant difference between the groups regarding the causes of explantation (p > 0.05). Among all the infected ears, 50% of them were infected by skin bacteria.
CONCLUSIONS: This multicenter study presents regional data on post- CI explantation in patients with NPC after radiotherapy. While explantation rates were four times higher in the NPC group, no single definitive cause beyond prior radiation exposure could be identified.
METHODS: This was a retrospective multicentre case-control study, which conducted on adults who underwent CI between 1994 and 2024. The rate, reasons and time after implantation of cochlear device explantation, and reimplantation rate were compared.
RESULTS: A total of 1067 ears (122 ears of NPC and 945 ears of non-NPC) were included in the study. The explantation rate was significantly higher in NPC group with a percentage of 7.38% compared with 2.01% in non-NPC group (p < 0.001, OR = 3.908). There was no significant difference between the groups regarding the causes of explantation (p > 0.05). Among all the infected ears, 50% of them were infected by skin bacteria.
CONCLUSIONS: This multicenter study presents regional data on post- CI explantation in patients with NPC after radiotherapy. While explantation rates were four times higher in the NPC group, no single definitive cause beyond prior radiation exposure could be identified.