[Age-related features of inflammatory and immune responses of the gastric mucosa in women with chronic gastritis].

The paper presents the results of studies of the specific features of an inflammatory reaction of the mucosa in the gastric body and antrum in chronic gastritis associated with Helicobacter pylori (HP) in females of reproductive age and in menopause. In the gastric body, there were prevalent chronic inflammatory processes with developed mononuclear infiltration in reproductive females whereas there were predominant elements of exudative and destructive inflammation in older females. The antral mucosa of young females showed predominantly destructive changes. The magnitude of HP seeding in the superficial and fossular mucosa was much higher both in the fundum and antrum in menopausal than reproductive females. There was great differences in the nature of inflammatory and immune reactions in either females with HP-associated chronic gastritis.