Acta endocrinologica (Bucharest, Romania : 2005) · 2022
PREDICTORS OF MULTIFOCAL PAPILLARY THYROID CANCER. DO THEY EXIST?
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Mazur O V, Palamarchuk V A, Tovkai O A, Kuts V V, Shidlovskyi V O, Sheremet M I, Levchuk R D, Morozovych I I, Lazaruk O V, Cretoiu D
Аннотация
UNLABELLED: The aim of this study is to analyze and identify the main predictors that may indicate multifocal growth of PTC.
MATERIALS AND METHODS: The main and control groups included patients with the category of malignant multifocal process T1-3mN0Mx (n=109) and unifocal T1-T3N0Mx (n=50) respectively, who underwent thyroidectomy with lymphadenectomy.Ultrasound characteristics of the nodes, tissue changes of the thyroid gland were taken into account.
RESULTS: Fibrous changes can be considered as one of the risk factors of the presence of additional PTC lesion.
DISCUSSION: There is no unambiguity in the definition of predictors of multifocal PTC growth.
CONCLUSIONS: No clear predictors of multifocal PTC have been identified. It is advisable to improve the quality of ultrasound, to focus on single-focus PTC in patients with fibrinous changes in the thyroid gland at normal levels of TSH.
MATERIALS AND METHODS: The main and control groups included patients with the category of malignant multifocal process T1-3mN0Mx (n=109) and unifocal T1-T3N0Mx (n=50) respectively, who underwent thyroidectomy with lymphadenectomy.Ultrasound characteristics of the nodes, tissue changes of the thyroid gland were taken into account.
RESULTS: Fibrous changes can be considered as one of the risk factors of the presence of additional PTC lesion.
DISCUSSION: There is no unambiguity in the definition of predictors of multifocal PTC growth.
CONCLUSIONS: No clear predictors of multifocal PTC have been identified. It is advisable to improve the quality of ultrasound, to focus on single-focus PTC in patients with fibrinous changes in the thyroid gland at normal levels of TSH.