Annali italiani di chirurgia · 2011
Abrikossoff tumor: does it origin in swchann cells? Case report.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Tarallo Mauro, Cigna Emanuele, Fino Pasquale, Lo Torto Federico, Pollastrini Alessia, Scuderi Nicolò
Аннотация
BACKGROUND: Abrikossoff tumor is an uncommon neoplasia, benign in most of the cases, that affects soft tissues, skin, and oral mucosa. Between 1% and 2% of cases are malignant and, in these cases, outcome is usually fatal. Between 5% and 25% of patients have multiple lesions.
CASE REPORT: A 52-year old Caucasian male was referred to the Plastic Surgery Department with a lesion in the tongue. A wide surgical excision was subsequently performed and the final pathologic diagnosis was Abrikossoff's tumor.
DISCUSSION: The pathogenesis of this tumor has long been subject of research and debate, and its origin has still to be clearly established. At the time, Abrikossoff proposed a myogenic origin, later studies supported a neural differentiation. According to the data in the literature the expression of S-100, that we found in our case, sustains the hypothesis that Abrikossoff tumor has origin in the Schwann's cells.
CONCLUSIONS: In our opinion, Abrikossoff tumor has origin in the Schwann's cells. However familial cases, congenital cases, and multiple lesions are uncommon, and it is worth stressing that this tumor has a good prognosis but every patient with Abrikossoff tumor should undergo a complete physical examination to rule out the presence of multiple associated tumors and possible visceral involvement.
CASE REPORT: A 52-year old Caucasian male was referred to the Plastic Surgery Department with a lesion in the tongue. A wide surgical excision was subsequently performed and the final pathologic diagnosis was Abrikossoff's tumor.
DISCUSSION: The pathogenesis of this tumor has long been subject of research and debate, and its origin has still to be clearly established. At the time, Abrikossoff proposed a myogenic origin, later studies supported a neural differentiation. According to the data in the literature the expression of S-100, that we found in our case, sustains the hypothesis that Abrikossoff tumor has origin in the Schwann's cells.
CONCLUSIONS: In our opinion, Abrikossoff tumor has origin in the Schwann's cells. However familial cases, congenital cases, and multiple lesions are uncommon, and it is worth stressing that this tumor has a good prognosis but every patient with Abrikossoff tumor should undergo a complete physical examination to rule out the presence of multiple associated tumors and possible visceral involvement.