Menopause (New York, N.Y.) · 2008
Endocrine regulation of the course of menopause by oral melatonin: first case report.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Diaz Beatriz Lopez, Llaneza Placido Coto
Аннотация
OBJECTIVE: The pineal gland, through its hormone melatonin, is involved in the mechanisms that regulate the aging process involved in the onset of menopause. Considering the melatonin changes reported during pre-, peri-, and postmenopause, an influence of melatonin on the hormonal changes associated with menopause transition could be expected.
DESIGN: We report the first longitudinal case study, covering a 7.5-year period, on the effects of melatonin administration on the reproductive hormones luteinizing hormone, follicle-stimulating hormone, and 17[beta]-estradiol during that period of the reproductive life.
RESULTS AND CONCLUSION: The data obtained in this case report show that melatonin administration was able to delay the characteristic endocrine changes that occur during the course of menopause.
DESIGN: We report the first longitudinal case study, covering a 7.5-year period, on the effects of melatonin administration on the reproductive hormones luteinizing hormone, follicle-stimulating hormone, and 17[beta]-estradiol during that period of the reproductive life.
RESULTS AND CONCLUSION: The data obtained in this case report show that melatonin administration was able to delay the characteristic endocrine changes that occur during the course of menopause.