Efficient primal-dual algorithm for imaging applications with matrix stacking, applied to DBT image reconstruction.

The primal-dual hybrid gradient (PDHG) algorithm for solving convex optimization problems that arise in tomographic imaging is revisited. In particular, simplification of the selection of step-size parameters is developed for optimization problems with multiple terms, each containing a linear transform subject to splitting. This simplification maintains algorithm efficiency while avoiding massive grid searches for the optimal parameter settings. The PDHG framework is demonstrated on an image reconstruction problem for wide-angle digital breast tomosynthesis (DBT); use of the proposed optimization problem is enabled by the framework and it is demonstrated to have some advantage in quantitative accuracy of the reconstructed volume and in improving DBT depth resolution.