Efficacy and Safety of Digital Single-Operator Cholangioscopy for Difficult Biliary Stones.
Обработка статьи · этапы, ошибки и управление
Ошибки и ограничения
История · было → стало
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Brewer Gutierrez Olaya I, Bekkali Noor L H, Raijman Isaac, Sturgess Richard, Sejpal Divyesh V, Aridi Hanaa D, Sherman Stuart, Shah Raj J, Kwon Richard S, Buxbaum James L, Zulli Claudio, Wassef Wahid, Adler Douglas G, Kushnir Vladimir, Wang Andrew Y, Krishnan Kumar, Kaul Vivek, Tzimas Demetrios, DiMaio Christopher J, Ho Sammy, Petersen Bret, Moon Jong Ho, Elmunzer B Joseph, Webster George J M, Chen Yen-I, Dwyer Laura K, Inamdar Summant, Patrick Vanessa B, Attwell Augustin, Hosmer Amy, Ko Christopher, Maurano Attilio, Sarkar Avik, Taylor Linda J, Gregory Martin H, Strand Daniel S, Raza Ali, Kothari Shivangi, Harris Jessica P, Kumta Nikhil A, Manvar Amar, Topazian Mark D, Lee Yun Nah, Spiceland Clayton M, Trindade Arvind J, Bukhari Majidah A, Sanaei Omid, Ngamruengphong Saowanee, Khashab Mouen A
Аннотация
METHODS: We performed a retrospective analysis of 407 patients (60.4% female; mean age, 64.2 years) who underwent D-SOC for difficult biliary stones at 22 tertiary centers in the United States, United Kingdom, or Korea from February 2015 through December 2016; 306 patients underwent electrohydraulic lithotripsy and 101 (24.8%) underwent laser lithotripsy. Univariate and multivariable analyses were performed to identify factors associated with technical failure and the need for more than 1 D-SOC electrohydraulic or laser lithotripsy session to clear the bile duct.
RESULTS: The mean procedure time was longer in the electrohydraulic lithotripsy group (73.9 minutes) than in the laser lithotripsy group (49.9 minutes; P < .001). Ducts were completely cleared (technical success) in 97.3% of patients (96.7% of patients with electrohydraulic lithotripsy vs 99% patients with laser lithotripsy; P = .31). Ducts were cleared in a single session in 77.4% of patients (74.5% by electrohydraulic lithotripsy and 86.1% by laser lithotripsy; P = .20). Electrohydraulic or laser lithotripsy failed in 11 patients (2.7%); 8 patients were treated by surgery. Adverse events occurred in 3.7% patients and the stone was incompletely removed from 6.6% of patients. On multivariable analysis, difficult anatomy or cannulation (duodenal diverticula or altered anatomy) correlated with technical failure (odds ratio, 5.18; 95% confidence interval, 1.26-21.2; P = .02). Procedure time increased odds of more than 1 session of D-SOC electrohydraulic or laser lithotripsy (odds ratio, 1.02; 95% confidence interval, 1.01-1.03; P < .001).
CONCLUSIONS: In a multicenter, international, retrospective analysis, we found D-SOC with electrohydraulic or laser lithotripsy to be effective and safe in more than 95% of patients with difficult biliary stones. Fewer than 5% of patients require additional treatment with surgery and/or extracorporeal shockwave lithotripsy to clear the duct.