[Bone disease with pain. Osteomyelitis in the long bone].

In the present time various antibiotics have been developed. But suppurative osteomyelitis has been very difficult to cure still up to now. If it fails to treat at the initial treatment, it recurs often. Many patients are annoyed by the recurrence. Moreover, increase of multiple resistance bacteria, opportunistic infection and traumatic osteomyelitis make them complex to treat. We have treated 256 osteomyelitis patients by debriding the infected area with closed irrigation before 1981. Then we have been treated 553 patients with Hyperbaric Oxygen Therapy (HBOT) . Include closed irrigation therapy, 95% of cases a good result occurred. The case that has fistula, sequestrum, foreign material or vast range of osteonecrosis is difficult to calm completely by only HBOT. In such cases, they should be taken curettage and closed irrigation.