[Role of autoimmune disorders in development of extrahepatic implications of chronic hepatitis C].

The materials received in the course of inspection of 104 patients with chronic hepatitis С are presented in article. In work it is shown that at patients with chronic hepatitis C the wide range of the autoantibodies which frequency of identification and expansion of their range is combined with emergence of biochemical signs and the subsequent clinical manifestation of the admixed cryoglobulinemia, and also accession of other extrahepatic implications is registered. The highest maintenance of the admixed cryoglobulins, rhematoid factor of IgM, circulating immune complexes in blood serum is registered at patients with existence of cliniko-biochemical signs of the HCV associated admixed cryoglobulinemia in combination with other extrahepatic implications.