Association Between the Atherogenic Index of Plasma and Sunburn: A Nationally Representative Study.

BACKGROUND

Research shows that sunburn is related to the inflammatory response caused by lipids. The atherogenic index of plasma (AIP) can evaluate the lipid profile through the interaction of different lipid components. However, whether AIP is related to the risk of sunburn has not been confirmed.

METHOD: The method is to include 11,241 National Health and Nutrition Examination Survey (NHANES) participants, and use multivariate logistic regression analysis to analyze the association between AIP and the risk of sunburn. Further subgroup analyses explored the correlation between AIP and sunburn, supplemented by interaction tests to assess model robustness. Additionally, restrictive cubic sample plots were examined to further investigate the nonlinear relationship between AIP and sunburn.

RESULTS

Multivariate logistic regression analysis revealed that individuals with higher AIP indices exhibited a higher prevalence of sunburn. Restricted cubic spline analysis demonstrated a positive linear dose-response relationship between AIP and sunburn. Subgroup analysis and interaction tests indicated that the positive correlation between AIP and sunburn prevalence was consistently observed across different populations (all p > 0.05).

CONCLUSION

There is a positive correlation between AIP and the risk and severity of sunburn. Future research needs to carry out longitudinal studies to determine the causal relationship.