International Evidence-Based Guidelines for Traditional Chinese Medicine Management of Allergic Rhinitis.
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Fu Qin-Wei, Liu Peng, Ruan Yan, Li Xin-Rong, Zhang Lan-Zhi, Yang Sha-Sha, Chai Feng, Chen Ji, Chen Qiao-Yan, Chen Shu-Cheng, Chen Wen-Yong, Chen Yong-Na, Cheng Hong-Bin, Cheng Lei, Cui Lu-Jia, Deng Ke-Bin, Fang Cai-Shan, Feng Rong-Chang, Fu Li, Fu Wen-Yang, Gao Jian-Ying, Guo Hong, He Miao, Hu Ko-Hsin, Huang Chun-Jiang, Huang He-Yin, Jiang Lu-Yun, Qiao Feng-Ying, Leng Hui, Li Yun-Ying, Liu Chun-Song, Liu Da-Xin, Liu Jian-Hua, Liu Jin-Hui, Liu Jing, Liu Min, Liu Wei-Ting, Liu Yuan-Xian, Liu Yang, Liu Ying, Liu Zhi-Qing, Luo Qiu-Lan, Ma Yu, Mao De-Hong, Meng Juan, Pang Kai-Yun, Peng Shun-Lin, Tong Xuan-Fu, Wang Ji, Wang Jia-Xi, Wang Jun-Ge, Wang Ren-Zhong, Wang Shi-Zhen, Xia Ji-Yan, Xie Hui, Xie Qiang, Xie Yan, Xiong Da-Jing, Yan Zhan-Feng, Yang Hui, Zhang Da-Zheng, Zhang Fu-Bing, Zhang Shi-Peng, Zhang Zhi-Cheng, Zhao Ji-Ping, Zhao Yu, Zheng Yun, Zhong Dan-Zhu, Zhou Li, Knyazev Valentin Mikhailovich, Kostrova Irina Viktorovna, Yeung Wing-Fai, Wang Qi, Wang De-Yun, Zhang Qin-Xiu
Аннотация
Allergic rhinitis (AR) is a prevalent chronic condition that significantly impacts patients' quality of life and poses challenges to effective management. Traditional Chinese medicine (TCM) offers a holistic approach, emphasizing syndrome differentiation, individualized care, and natural treatment strategies. To develop comprehensive evidence-based guidelines for AR management using TCM interventions, incorporating rigorous evidence assessment and expert consensus. The guidelines were developed using the GRADE-TCM framework, analyzing 351 randomized controlled trials (RCTs) involving 43,276 participants. Supplementary evidence from published textbooks, standardized documents, ancient literature, and TCM medical records was incorporated. Five rounds of expert consensus, involving 80 expert person-times and over 10,000 valid responses, refined the recommendations. The guidelines provide 32 recommendations covering four primary TCM syndromes (Deficiency-cold of Lung Qi, Spleen Qi Deficiency and Weakness, Kidney-yang Deficiency, and Latent Heat in Lung Meridian) which are mainly involved in AR. These recommendations include both internal interventions (such as herbal and patent medicines) and external therapies (such as acupuncture, moxibustion, and other acupoint-based treatment). Of these interventions, 10 received strong recommendations, while 22 were classified as weak recommendations. TCM treatments demonstrated significant efficacy in alleviating AR symptoms, reducing recurrence, and improving quality of life. Additionally, TCM can complement conventional AR treatments by reducing the need for pharmacological therapy while maintaining a favorable safety profile. The guidelines integrate classical TCM principles with modern evidence-based methodologies, offering a structured framework for AR management. They serve as clinical references for practitioners worldwide, supporting a promising approach to AR treatment. Future updates will incorporate emerging evidence and real-world clinical data to further optimize the role of TCM in AR management.