Head & neck · 2011
Relationship between paraglottic space invasion and cervical lymph node metastasis in patients undergoing supracricoid partial laryngectomy.
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Joo Young-Hoon, Park Jun-Ook, Cho Kwang-Jae, Kim Min-Sik
Аннотация
BACKGROUND: To investigate the relationship between paraglottic space (PGS) invasion and lymph node metastasis in patients undergoing supracricoid partial laryngectomy.
METHODS: The study included 98 subjects with squamous cell carcinoma of the glottis.
RESULTS: The PGS invasion rate was 60.2% (59/98), and a significant correlation was found between PGS invasion and cervical lymph node metastasis (p = .022). Fifteen of the 59 patients (25.4%) with PGS invasion, only 3 of the 39 patients (7.7%) without any evidence of PGS invasion had lymph node metastasis. Furthermore, a significant correlation was also found between PGS invasion and T classification (p < .001), vocal cord mobility (p < .001), and subglottic extension (p = .014), and patients with no evidence of PGS invasion possibly had a survival benefit (5-year disease-specific survival rate, 84% vs 64%; p = .118).
CONCLUSION: This study shows that PGS invasion is significantly related to cervical lymph node metastasis in patients undergoing supracricoid partial laryngectomy.
METHODS: The study included 98 subjects with squamous cell carcinoma of the glottis.
RESULTS: The PGS invasion rate was 60.2% (59/98), and a significant correlation was found between PGS invasion and cervical lymph node metastasis (p = .022). Fifteen of the 59 patients (25.4%) with PGS invasion, only 3 of the 39 patients (7.7%) without any evidence of PGS invasion had lymph node metastasis. Furthermore, a significant correlation was also found between PGS invasion and T classification (p < .001), vocal cord mobility (p < .001), and subglottic extension (p = .014), and patients with no evidence of PGS invasion possibly had a survival benefit (5-year disease-specific survival rate, 84% vs 64%; p = .118).
CONCLUSION: This study shows that PGS invasion is significantly related to cervical lymph node metastasis in patients undergoing supracricoid partial laryngectomy.