Head & neck · 2011
Modified type III cordectomy to improve voice outcomes after transoral laser microsurgery for early glottic canser.
Сравнительное исследованиеСтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
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Chu Pen-Yuan, Hsu Yen-Bin, Lee Tsung-Lun, Fu Sherry, Wang Li-Mei, Kao Ya-Chung
Аннотация
BACKGROUND: We proposed a modified type III cordectomy for the treatment of early glottic cancer that removed the upper part of the vocalis muscle to improve glottic closure and voice outcomes.
METHODS: Twenty-two patients with early glottic cancer underwent type III cordectomy, including 9 classical (proposed by European Laryngological Society) and 13 modified resections. Multidimensional voice evaluations were performed.
RESULTS: Voice parameters including GRBAS (overall grade [G], roughness of the voice [R], breathiness [B], asthenicity [A], and strain [S]), jitter, shimmer, noise-to-harmonic ratio, maximum phonation time, voice handicap index-functional, physical, and total scores were better in modified resection. Eleven patients (85%) had complete glottic closure in modified resection and 3 (33%) in classical resection (p = .026). Only 2 patients had tumor recurrence, 1 (8%) in the modified resection and 1 (11%) in the classical resection group (p = 1.000).
CONCLUSIONS: Modified type III cordectomy proved to be an oncologically safe method. The voice outcomes were better than those in patients who underwent classical type III cordectomy.
METHODS: Twenty-two patients with early glottic cancer underwent type III cordectomy, including 9 classical (proposed by European Laryngological Society) and 13 modified resections. Multidimensional voice evaluations were performed.
RESULTS: Voice parameters including GRBAS (overall grade [G], roughness of the voice [R], breathiness [B], asthenicity [A], and strain [S]), jitter, shimmer, noise-to-harmonic ratio, maximum phonation time, voice handicap index-functional, physical, and total scores were better in modified resection. Eleven patients (85%) had complete glottic closure in modified resection and 3 (33%) in classical resection (p = .026). Only 2 patients had tumor recurrence, 1 (8%) in the modified resection and 1 (11%) in the classical resection group (p = 1.000).
CONCLUSIONS: Modified type III cordectomy proved to be an oncologically safe method. The voice outcomes were better than those in patients who underwent classical type III cordectomy.
Предметные рубрики MeSH
AdultAgedAged, 80 and overAnalysis of VarianceBiopsy, NeedleChi-Square DistributionCohort StudiesFemaleFollow-Up StudiesGlottisHumansImmunohistochemistryLaryngeal NeoplasmsLaser TherapyMaleMicrosurgeryMiddle AgedNeoplasm StagingRetrospective StudiesRisk AssessmentStatistics, NonparametricTreatment OutcomeVocal CordsVoice Quality