Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC · 2014
Tubal teratoma causing anti-NMDAR encephalitis.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Power Laura, James Joann, Masoud Ibtisam, Altman Alon
Аннотация
BACKGROUND: Anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis is considered a rare autoimmune disorder usually caused by an ovarian teratoma. The disease is clinically characterized by neuropsychiatric symptoms followed by intractable seizures and hypoventilation, and it is fatal if left untreated.
CASE: We present a case of anti-NMDAR encephalitis with classical features in a young woman whose ultimate diagnosis and treatment were delayed because of multiple avoidable circumstances that were recognized only in retrospect.
CONCLUSION: We believe that this disorder is actually more common than reported. Anti-NMDAR encephalitis must be considered as part of the differential diagnosis in any young woman presenting with new onset psychiatric symptoms. In young women with an acute decrease in their level of consciousness, prompt and continued surveillance for the presence of an underlying tumour should be undertaken, especially when there is a delayed response to empiric treatment.
CASE: We present a case of anti-NMDAR encephalitis with classical features in a young woman whose ultimate diagnosis and treatment were delayed because of multiple avoidable circumstances that were recognized only in retrospect.
CONCLUSION: We believe that this disorder is actually more common than reported. Anti-NMDAR encephalitis must be considered as part of the differential diagnosis in any young woman presenting with new onset psychiatric symptoms. In young women with an acute decrease in their level of consciousness, prompt and continued surveillance for the presence of an underlying tumour should be undertaken, especially when there is a delayed response to empiric treatment.