Serological diagnosis of infection by Helicobacter pylori in chronic ulcer disease.

The authors estimated the frequency of occurrence of the infection by Helicobacter pylori in the long term gastroduodenal ulcer disease. The serological diagnosis (ELISA test) was carried out in 175 patients, suffering from this disease for at least two years, to reveal the existence of specific IgG against Helicobacter pylori. The study confirmed the frequent occurrence of infection by Helicobacter pylori in the gastro-duodenal ulcer disease of the stomach (59.2%) and the duodenum (83.7%). It was found that mainly in men the existence of specific IgG against Helicobacter pylori (in the ulcer of the stomach 63.3% and in the ulcer of the duodenum 89.9%!). The results indicate the necessity of taking into consideration the infection by Helicobacter pylori in the treatment of perennial gastro-duodenal ulcer disease.