Acute pancreatitis in Turkey: Results of a nationwide multicenter study.
Обработка статьи · этапы, ошибки и управление
Ошибки и ограничения
История · было → стало
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Köksal Aydın Şeref, Tozlu Mukaddes, Sezgin Orhan, Oğuz Dilek, Kalkan İsmail Hakkı, Altıntaş Engin, Yaraş Serkan, Bilgiç Yılmaz, Yıldırım Abdullah Emre, Barutçu Sezgin, Hakim Gözde Derviş, Soytürk Müjde, Bengi Göksel, Özşeker Burak, Yurci Alper, Koç Deniz Öğütmen, İrak Kader, Kasap Elmas, Cindoruk Mehmet, Oruç Nevin, Ünal Nalan Gülşen, Şen İlker, Gökden Yasemin, Saruç Murat, Ünal Hakan, Eminler Ahmet Tarık, Toka Bilal, Basır Hakan, Sağlam Osman, Ergül Bilal, Gül Özlem, Büyüktorun İlker, Özel Mustafa, Şair Ümit, Kösem Gizem, Nedirli Ferda, Tahtacı Mustafa, Parlak Erkan
Аннотация
METHODS: All patients with AP who were hospitalized at 17 tertiary centers in Turkey between April and October 2022 were evaluated in a prospective cohort study. Patients with insufficient data, COVID-19 and those aged below 18 years were excluded. The definitions were based on the 2012 revised Atlanta criteria.
RESULTS: The study included 2144 patients (median age:58, 52 % female). The most common etiologies were biliary (n = 1438, 67.1 %), idiopathic (n = 259, 12 %), hypertriglyceridemia (n = 128, 6 %) and alcohol (n = 90, 4.2 %). Disease severity was mild in 1567 (73.1 %), moderate in 521 (24.3 %), and severe in 58 (2.6 %) patients. Morphology was necrotizing in 4.7 % of the patients. The overall mortality rate was 1.6 %. PASS and BISAP had the highest accuracy in predicting severe pancreatitis on admission (AUC:0.85 and 0.81, respectively). CT was performed in 61 % of the patients, with the majority (90 %) being within 72 h after admission. Prophylactic NSAIDs were not administered in 44 % of the patients with post-ERCP pancreatitis (n = 86). Antibiotics were administered to 53.7 % of the patients, and 38 % of those received them prophylactically.
CONCLUSIONS: This prospective study provides an extensive report on clinical characteristics, management and outcomes of AP in real-world practice. Mortality remains high in severe cases and physicians' adherence to guidelines during management of the disease needs improvement in some aspects.