Neurosurgery · 1997
Granulocytic sarcoma of the spine in nonleukemic patients: report of three cases.
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Deme S, Deodhare S S, Tucker W S, Bilbao J M
Аннотация
OBJECTIVE AND IMPORTANCE: Granulocytic sarcomas involving the spine in patients without myelogenous leukemia are rare. We report three cases and review the literature.
CLINICAL PRESENTATION: Three patients presented with spinal epidural tumors, which caused spinal cord compression in one and cauda equina compression in two.
INTERVENTION: All patients underwent surgery, and biopsies revealed histological features of granulocytic sarcomas. Bone marrow aspirates and biopsies showed no evidence of acute leukemia at initial presentation, for all three patients.
CONCLUSION: Granulocytic sarcomas in nonleukemic patients are rare, and when they affect the spine they are frequently misdiagnosed. Appropriate therapy for these tumors requires early identification.
CLINICAL PRESENTATION: Three patients presented with spinal epidural tumors, which caused spinal cord compression in one and cauda equina compression in two.
INTERVENTION: All patients underwent surgery, and biopsies revealed histological features of granulocytic sarcomas. Bone marrow aspirates and biopsies showed no evidence of acute leukemia at initial presentation, for all three patients.
CONCLUSION: Granulocytic sarcomas in nonleukemic patients are rare, and when they affect the spine they are frequently misdiagnosed. Appropriate therapy for these tumors requires early identification.
Предметные рубрики MeSH
AdolescentAdultBone MarrowBone Marrow TransplantationCauda EquinaChemotherapy, AdjuvantCombined Modality TherapyDiagnosis, DifferentialEpidural NeoplasmsFatal OutcomeGranulocytesHumansLeukemia, MyeloidMagnetic Resonance ImagingMaleMiddle AgedNeoplasm Recurrence, LocalNerve Compression SyndromesRadiotherapy, AdjuvantSpinal Cord CompressionTomography, X-Ray Computed