Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics · 2009
Subgemmal neurogenous plaque: clinical and microscopic evaluation of 7 cases.
Клинический случайСтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Gueiros Luiz Alcino, León Jorge Esquiche, Leão Jair Carneiro, Lopes Márcio Ajudarte, Jorge Jacks, de Almeida Oslei Paes
Аннотация
Subgemmal neurogenous plaques (SNPs) are biphasic neural structures found on the posterolateral border of the tongue. Fewer than 40 cases have been reported and only a few were symptomatic. The present report details the features of 7 cases of SNP retrieved from the files of a single institution. Clinical and histopathological data were reviewed and immunohistochemical analysis was performed for S100, CD56, neuron-specific enolase, epithelial membrane antigen, CK7, CK8, CK14, and CK20. All cases showed similar morphological and immunohistochemical characteristics. Neural markers highlighted the biphasic pattern and CK7, CK8, and CK20 were detected on taste buds confined to the epithelium adjacent to the SNPs. Five patients presented pain/discomfort as the main symptom. Symptomatic SNPs seems to be more common than previously reported, presenting as focal burning on the posterolateral border of the tongue.