Naldemedine for opioid-induced constipation.

Generic name: Naldemedine tosylate Brand name: Rizmoic Formulation: 200 mcg film-coated tablets Market Authorisation holder: Shionogi B.V Indication: Treatment of opioid-induced constipation in adult patients who have previously been treated with a laxative Dose: 200 mcg/day, taken at the same time every day. Naldemedine may be used with or without a laxative. It must be discontinued if treatment with the opioid is discontinued. Cost: £41.72 for 28 tablets Classification: Prescription only medicine subject to additional monitoring (▼).