Anticancer research · 2018
Comparison of Primary Tumor Size in Stage I and III Epithelial Ovarian Cancer.
Сравнительное исследованиеСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Petru Edgar, Huber Carola, Sampl Eva, Haas Josef
Аннотация
BACKGROUND: Two studies have found primary ovarian carcinomas in stage I disease to be larger than those in stage III. Thus, these stages may represent different tumor entities.
MATERIALS AND METHODS: The clinical data from 553 patients operated on between 1985 and 2012 for epithelial ovarian cancer were retrospectively analyzed.
RESULTS: Primary lesions including invasive, borderline and benign components were significantly larger in stage I compared to stage III disease (p<0.001). However, the maximum diameter of invasive components in those with stage III disease were significantly larger than in those with stage I disease (p=0.001). The size of the invasive component was not associated with the largest size of intraperitoneal metastasis.
CONCLUSION: We were only, in part, able to reproduce the data from the two smaller published studies. The prognosis of patients with stage III disease strongly depends on the size of intraperitoneal metastases.
MATERIALS AND METHODS: The clinical data from 553 patients operated on between 1985 and 2012 for epithelial ovarian cancer were retrospectively analyzed.
RESULTS: Primary lesions including invasive, borderline and benign components were significantly larger in stage I compared to stage III disease (p<0.001). However, the maximum diameter of invasive components in those with stage III disease were significantly larger than in those with stage I disease (p=0.001). The size of the invasive component was not associated with the largest size of intraperitoneal metastasis.
CONCLUSION: We were only, in part, able to reproduce the data from the two smaller published studies. The prognosis of patients with stage III disease strongly depends on the size of intraperitoneal metastases.