[Atypical picture of familial medullary thyroid carcinoma].

Two sisters are reported treated at various times for thyroid medullary carcinoma. In one of them, treated later, right adrenal tumour coexisted suggesting a classical picture of the syndrome of multiglandular endocrine adenomatosis type 2a. Histological examination of the adrenal tumour showed presence of metastasis of medullary thyroid carcinoma, that is atypical pattern of this neoplasm. In the light of these the authors stress the necessity of comprehensive diagnosis of thyroid tumours with particular stress laid on histological preoperative diagnosis. Indications are discussed to thyroid reoperation in patients in whom medullary thyroid carcinoma was diagnosed only in the resected goitre.