Journal of clinical laboratory analysis · 2022
Post-radiotherapy cribriform-morular thyroid carcinoma.
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Or Koca Arzu, Güler Şimşek Gülçin
Аннотация
BACKGROUND: According to the new 2022 World Health Organization classification of endocrine tumors, thyroid malignancy, formerly known as the cribriform-morular variant of papillary thyroid carcinoma, is now categorized as differentiated thyroid malignancy; it is, at present, called cribriform-morular thyroid carcinoma and classified as a tumor of unknown histogenesis.
CASE REPORT: In this case report, we report on a 15-year-old patient who underwent external radiotherapy to the neck for Hodgkin's disease and developed cribriform-morular thyroid carcinoma 5 years after radiotherapy.
CONCLUSIONS: We believe that cribriform-morular thyroid carcinoma with diffuse nuclear beta-catenin expression has exciting and unresolved uncertainties that may affect disease prognosis and follow-up for cytopathologists and endocrinologists.
CASE REPORT: In this case report, we report on a 15-year-old patient who underwent external radiotherapy to the neck for Hodgkin's disease and developed cribriform-morular thyroid carcinoma 5 years after radiotherapy.
CONCLUSIONS: We believe that cribriform-morular thyroid carcinoma with diffuse nuclear beta-catenin expression has exciting and unresolved uncertainties that may affect disease prognosis and follow-up for cytopathologists and endocrinologists.