["Magic bullets"--monoclonal antibodies in acute leukemia and non-Hodgkin's lymphoma treatment].

Because of high percent of failures in haematologic malignancies treatment there is a need of discovering new drugs. One of the new approaches are monoclonal antibodies, which target specific cluster differentiation antigens on tumor cells. Rituximab is an anti-CD20 antibody used in non-Hodgkin lymphoma, alemtuzumab--in B chronic lymphocytic leukaemia, gemtuzumab ozogamicin--in non-lymphoblastic leukaemia, tositumomab and ibritumomab are monoclonal antibodies binded with radiopharmaceutics and are used in non-Hodgkin lymphomas.