Spindle Cell Lipoma in the Lower Lip: A Report of a Rare Case in Plastic Surgery.

Spindle cell lipoma (SCL) is a rare subtype of lipoma. SCL is commonly reported in subcutaneous tissues of the neck, shoulders, and back, but its occurrence in the lip, where adipose tissue is sparse, is rare. We present a case of SCL in a 53-year-old woman referred to our plastic surgery department with a chief complaint of a submucosal mass in the right lower lip. Magnetic resonance imaging (MRI) revealed a mass in the submucosal tissue of the lower lip. Surgical excision was performed through a lip incision. Histopathological examination confirmed the diagnosis of SCL with the presence of CD34-positive/S100-negative cells. Differential diagnosis between SCL and liposarcoma is crucial and challenging based on clinical or imaging findings, emphasizing the importance of histopathological examination.