Acta paediatrica (Oslo, Norway : 1992) · 2026
Effects of Immediate Skin-to-Skin Contact in Preterm Infants in High-Resource Settings: A Systematic Review.
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Rettedal Victoria, Rettedal Siren, Rytter Maren Johanne Heilskov, Larsen Linea Grothe, Buskov Frederikke, Mörelius Evalotte, Mehler Katrin, Lode-Kolz Karoline
Аннотация
AIM: A landmark trial published in 2021 demonstrated a 25% reduction in neonatal mortality when comparing immediate skin-to-skin contact (iSSC) to conventional care in infants with birthweight 1-1.8 kg in low- and middle-resource settings. New evidence from randomised clinical trials on iSSC in high-resource settings has recently become available. This systematic review aimed to evaluate evidence for immediate/early SSC, defined as initiated within 1 h after birth, versus conventional care in inborn preterm infants in high-resource settings.
METHODS: Ten electronic databases, including PubMed, Embase, and Cochrane CENTRAL, from 2000 until February 2026, were searched. Randomised clinical trials comparing iSSC to conventional care in inborn preterm infants in high-resource settings were included.
RESULTS: Four randomised clinical trials encompassing 325 infants were included. iSSC was feasible and safe. Cardiorespiratory stability, thermoregulation, breastfeeding practices, maternal-infant interaction, infant stress regulation, and parental mental health outcomes were in favour of the intervention.
CONCLUSIONS: This systematic review provides updated evidence on the effectiveness of iSSC for preterm infants admitted to neonatal intensive care units in high resource settings. The findings support that there is a sensitive window in the first hours after birth when preterm infants and parents should not be separated.
METHODS: Ten electronic databases, including PubMed, Embase, and Cochrane CENTRAL, from 2000 until February 2026, were searched. Randomised clinical trials comparing iSSC to conventional care in inborn preterm infants in high-resource settings were included.
RESULTS: Four randomised clinical trials encompassing 325 infants were included. iSSC was feasible and safe. Cardiorespiratory stability, thermoregulation, breastfeeding practices, maternal-infant interaction, infant stress regulation, and parental mental health outcomes were in favour of the intervention.
CONCLUSIONS: This systematic review provides updated evidence on the effectiveness of iSSC for preterm infants admitted to neonatal intensive care units in high resource settings. The findings support that there is a sensitive window in the first hours after birth when preterm infants and parents should not be separated.