Archives of medical science : AMS · 2021
Radical surgical treatment of neuroendocrine tumors of the appendix in children - a Polish multicenter study.
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Panek Małgorzata, Szymczak Marek, Stepaniuk Maria, Górecki Wojciech, Gawłowska-Marciniak Aleksandra, Wolak Przemysław, Zbyrad Dariusz, Rybkiewicz Marek, Chrobak Kamila, Noparlik Ryszard, Niedzielski Jerzy, Janik Przemysław, Nowak Jan, Miaśkiewicz Witold, Kamiński Andrzej, Fischer Wojciech, Dembowska-Bagińska Bożena, Kaliciński Piotr
Аннотация
INTRODUCTION: The aim of the study was to examine management of pediatric appendiceal neuroendocrine tumors (ANETs) in Poland.
METHODS: Records of 27 patients with ANET diagnosed incidentally after appendectomy in the last decade.
RESULTS: Well-differentiated NET G1/G2 was diagnosed in 25 and well-differentiated neuroendocrine carcinoma G3 in 2 patients. Extended surgery was performed primarily in one instance and secondarily in 10 patients (right hemicolectomy in 9, ileocecal resection in 1) without adjuvant chemotherapy. Follow-up range was 1-121 months. Recurrence after secondary surgery was observed in 1 (3.7%) patient.
CONCLUSIONS: Applying ENETS guidelines resulted in 100% overall survival of patients with NET.
METHODS: Records of 27 patients with ANET diagnosed incidentally after appendectomy in the last decade.
RESULTS: Well-differentiated NET G1/G2 was diagnosed in 25 and well-differentiated neuroendocrine carcinoma G3 in 2 patients. Extended surgery was performed primarily in one instance and secondarily in 10 patients (right hemicolectomy in 9, ileocecal resection in 1) without adjuvant chemotherapy. Follow-up range was 1-121 months. Recurrence after secondary surgery was observed in 1 (3.7%) patient.
CONCLUSIONS: Applying ENETS guidelines resulted in 100% overall survival of patients with NET.