The clinical features and prognosis of hepatoblastoma: follow-up studies done on pediatric tumors enrolled in the Japanese Pediatric Tumor Registry between 1971 and 1980. Part I. Committee of Malignant Tumors, Japanese Society of Pediatric Surgeons.

Retrospective follow-up studies were conducted on 101 cases of hepatoblastoma enrolled in the registry established by the Committee of Malignant Tumors of the Japanese Society of Pediatric Surgeons between 1971 and 1980. The disease was classified into the following 5 categories; namely, stages I, II, IIIA, IIIB and IV according to local involvement (factor C), vascular invasion (factor V), lymph node involvement (factor N), and distant metastasis (factor M). The results were analysed as the relation between two-year tumor-free survival rate (2YTFSR) and various factors. The overall 2YTFSR of 42 per cent was found to be related to the staging system, age and quality of resection, and our results indicated that cure could be achieved by complete resection of the tumor.