Ameloblastic Fibro-odontoma - A Case Report of Two Uncommon Cases.

RATIONALE: Ameloblastic fibro-odontoma (AFO) is a rare mixed odontogenic tumour with a preferential location in the posterior mandible and with a variety of radiological aspects. We report two clinical cases of AFO in two rare locations and with unusual radiological aspects.

PATIENT CONCERNS: The first patient is a 37-year-old female with an asymptomatic intraoral swelling located in the anterior mandibular. The second patient is a 16-year-old girl with a chief complaint of missing maxillary canine.

DIAGNOSIS: Both cases were diagnosed with AFO.

TREATMENT: For the first patient, a biopsy was performed, and for the second one, the lesion was surgically excised.

OUTCOMES: The first patient is under regular surveillance and the other was followed up for one year without any evidence of recurrences.

TAKE-AWAY LESSONS: Despite many efforts, the nature, histology and therapy of these lesions remain very confusing.