Arkhiv patologii · 2014
[Blood rheological characteristics of uteroplacental blood flow in severe gestosis].
Аннотация на английскомСтатьяНазвание и аннотация: Оригинал на русском
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Pavlova T V, Petrukhin V A, Sumin S A, Selivanova A V, Syrtseva I S
Аннотация
OBJECTIVE: To investigate the clinical and morphological features of uteroplacental blood flow during pregnancy in severe gestosis.
SUBJECTS AND METHODS: One hundred and twenty-five patients with severe gestosis were examined. Scanning probe and electron microscopy with macro- and microelement analysis and transmission microscopy were used to study their placentas, umbilical cords, endometrium, myometrium, and maternal blood in severe gestosis.
RESULTS: It is shown that circulatory disorders in the structural components of the examined tissues and organs, as well as changes in cytoarchitectonics and red blood cell functional properties may be a component of the trigger of disseminated intravascular coagulation, followed by impaired maternal and fetal vital activity.
CONCLUSION: The investigation of the pathomorphological features of the microcirculatory bed in the mother-placenta-fetus system in gestosis has shown that possible methods of their correction should be further sought.
SUBJECTS AND METHODS: One hundred and twenty-five patients with severe gestosis were examined. Scanning probe and electron microscopy with macro- and microelement analysis and transmission microscopy were used to study their placentas, umbilical cords, endometrium, myometrium, and maternal blood in severe gestosis.
RESULTS: It is shown that circulatory disorders in the structural components of the examined tissues and organs, as well as changes in cytoarchitectonics and red blood cell functional properties may be a component of the trigger of disseminated intravascular coagulation, followed by impaired maternal and fetal vital activity.
CONCLUSION: The investigation of the pathomorphological features of the microcirculatory bed in the mother-placenta-fetus system in gestosis has shown that possible methods of their correction should be further sought.