[Emphasis the early diagnosis and treatment of plasma cell disease-related kidney disease].

Plasma cell disorders represent a spectrum of complex diseases, ranging from benign conditions to malignancies. The monoclonal immunoglobulins produced in these disorders can result in various renal pathologies, which may present as differing degrees of renal insufficiency. In severe instances, patients may necessitate dialysis or kidney transplantation. The recovery of kidney damage is relatively delayed after treatment. Some patients achieved hematological complete response, but kidney impairment may progressively worsen. Clinicians need to be more vigilant and pay more attention to PCD related kidney impairment. Early diagnosis and treatment are of great significance for reversing renal dysfunction and improving survival.