In vivo (Athens, Greece) · 2020
COVID-19 Incidentally Detected on PET/CT During Work-up for Locally Advanced Head and Neck Cancer.
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Mo Allen, Brodin N Patrik, Tomé Wolfgang A, Garg Madhur K, Kabarriti Rafi
Аннотация
AIM: To describe the incidental detection of COVID-19 disease on positron-emission tomography/computed tomography (PET/CT) in a patient with cancer despite initial negative swab by polymerase chain reaction (PCR).
CASE REPORT: Clinical and radiographic data were obtained from the electronic medical record. Nasopharyngeal swabs were obtained and evaluated for COVID-19 by the Food and Drug Administration-approved reverse transcription-PCR assays. On radiographic examination, PET/CT was consistent with COVID-19-related pneumonia not seen on prior imaging. Initial nasopharyngeal swab 2 days after PET/CT imaging was negative for COVID-19. Subsequent repeat swab 10 days later was positive for COVID-19, while the patient was febrile on screening assessment. The patient remained COVID-19-positive until 1 month after abnormal PET/CT imaging.
CONCLUSION: PET/CT can be sensitive for early COVID-19 detection, even in the setting of a negative confirmatory PCR test. This highlights the importance of continued patient surveillance and use of appropriate personal protective equipment to minimize COVID-19 transmission.
CASE REPORT: Clinical and radiographic data were obtained from the electronic medical record. Nasopharyngeal swabs were obtained and evaluated for COVID-19 by the Food and Drug Administration-approved reverse transcription-PCR assays. On radiographic examination, PET/CT was consistent with COVID-19-related pneumonia not seen on prior imaging. Initial nasopharyngeal swab 2 days after PET/CT imaging was negative for COVID-19. Subsequent repeat swab 10 days later was positive for COVID-19, while the patient was febrile on screening assessment. The patient remained COVID-19-positive until 1 month after abnormal PET/CT imaging.
CONCLUSION: PET/CT can be sensitive for early COVID-19 detection, even in the setting of a negative confirmatory PCR test. This highlights the importance of continued patient surveillance and use of appropriate personal protective equipment to minimize COVID-19 transmission.
Предметные рубрики MeSH
Asymptomatic DiseasesBetacoronavirusCOVID-19COVID-19 TestingCarcinoma, Squamous CellClinical Laboratory TechniquesCoronavirus InfectionsFalse Negative ReactionsHumansIncidental FindingsInfectious Disease Transmission, Patient-to-ProfessionalMaleMiddle AgedNasopharynxNew York CityPandemicsPneumonia, ViralPositron Emission Tomography Computed TomographyProtective DevicesReverse Transcriptase Polymerase Chain ReactionSARS-CoV-2Sensitivity and SpecificityTonsillar Neoplasms