BMC pulmonary medicine · 2026
Yellow nail syndrome: a syndrome with prominent manifest involvement of the respiratory system.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Wang Ying, Ren Juan, Mao Congzheng, Qiu Huaiming, Meng Beibei, Cai Xiaoyu, Yang Bo, Liu Haichao, Hu Zhenhong, Fang Yao
Аннотация
BACKGROUND: Yellow Nail Syndrome (YNS) is a rare disorder characterized by the classic triad of yellow nails, lymphedema, and chronic respiratory involvement.
CASE PRESENTATION: We report a 42-year-old male with YNS and childhood-onset symptoms lasting for over three decades. He presented with refractory, recurrent chylothorax that progressed to organized pleural effusion and pleural calcification, complicated by respiratory failure and pericardial effusion. Systemic lymphangiography confirmed severe lymphatic reflux and obstruction.
CONCLUSION: This case highlights the diagnostic and therapeutic challenges of YNS, which often leads to underdiagnosis. Clinicians should screen for extrapulmonary signs, including yellow nails and lymphedema, in patients with unexplained pleural effusion to facilitate early diagnosis and intervention and prevent irreversible disease progression.
SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12890-026-04172-8.
CASE PRESENTATION: We report a 42-year-old male with YNS and childhood-onset symptoms lasting for over three decades. He presented with refractory, recurrent chylothorax that progressed to organized pleural effusion and pleural calcification, complicated by respiratory failure and pericardial effusion. Systemic lymphangiography confirmed severe lymphatic reflux and obstruction.
CONCLUSION: This case highlights the diagnostic and therapeutic challenges of YNS, which often leads to underdiagnosis. Clinicians should screen for extrapulmonary signs, including yellow nails and lymphedema, in patients with unexplained pleural effusion to facilitate early diagnosis and intervention and prevent irreversible disease progression.
SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12890-026-04172-8.