Медицинская библиотека · Therapeutic advances in endocrinology and metabolism · 2025

Lipid accumulation product and visceral adiposity index in women with and without polycystic ovary syndrome: a systematic review and meta-analysis.

Ulloque-Badaracco Juan R, Hernandez-Bustamante Enrique A, Cabrera-Guzmán Juan C, Delgado-Raygada Jose E, Dotto-Vasquez Giuseppe, Maldonado-Basurto Gian F, Figueroa-Larragán Alberto A, Trujillo-Jurado Katherin Z, Evaristo-Ballmann Gustavo, Flores-Gavino Aldo, Herrera-Añazco Percy, Benites-Zapata Vicente A

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Аннотация

BACKGROUND

Polycystic ovary syndrome (PCOS) is a chronic, heterogeneous and prevalent endocrine-metabolic condition.

OBJECTIVES

This study aims to synthesize the available evidence on the comparison of lipid accumulation product (LAP) and visceral adiposity index (VAI) in women with and without PCOS.

DESIGN

Systematic review and meta-analysis.

DATA SOURCES AND

METHODS

A systematic search was executed across five electronic databases. Continuous variables were assessed using the standardized mean difference (SMD) and its 95% confidence interval (CI).

RESULTS

A total of 46 studies were included (n = 12,442). PCOS patients have higher values of LAP (n = 10,658; SMD: 0.65; 95% CI: 0.47-0.83, p < 0.05; I 2 = 93.65%) and VAI (n = 7930; SMD: 0.53; 95% CI: 0.21-0.85; p < 0.05; I 2 = 97.24%) compared to those without the syndrome.

CONCLUSION

Women with PCOS show significantly higher VAI and LAP values than those without this syndrome.

Для цитирования: Ulloque-Badaracco Juan R, Hernandez-Bustamante Enrique A, Cabrera-Guzmán Juan C, Delgado-Raygada Jose E, Dotto-Vasquez Giuseppe, Maldonado-Basurto Gian F, Figueroa-Larragán Alberto A, Trujillo-Jurado Katherin Z, Evaristo-Ballmann Gustavo, Flores-Gavino Aldo, Herrera-Añazco Percy, Benites-Zapata Vicente A. Lipid accumulation product and visceral adiposity index in women with and without polycystic ovary syndrome: a systematic review and meta-analysis.. Therapeutic advances in endocrinology and metabolism. 2025. DOI: 10.1177/20420188251397203.

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