38-year-old woman with nasal congestion: A rare case of septum-originated benign fibrous histiocytoma.

INTRODUCTION

Benign fibrous histiocytoma (BFH) is a mesenchymal tumor composed of fibroblasts and histiocytes, which normally occurs in the bone tissue and/or the skin of the limbs. BFH of the nasal septum is rare worldwide.

PATIENT CONCERNS: A 38-year-old female patient attended our clinic with congestion in her right nasal cavity.

DIAGNOSES: Endoscopic examination revealed a mass within the right nasal passage. Immunohistochemical staining demonstrated cells labeled with VIM (+), CD68PGM1 (+), CD34 (-), Actin (-), PCK (-), EMA (-), Desmin (-), SMA (-), S-100 (-), P63 (-), ALK-1 (-), beta-catenia (+), and KI67 (+). Clinical and histopathological examinations showed that the mass was a septum-originated BFH.

INTERVENTIONS: For the treatment of BFH of the nasal septum, the mass was removed endoscopically using a transnasal approach.

OUTCOMES: No recurrence was observed over 30 months of follow-up.

CONCLUSION

To prevent the recurrence wide local resection with histological clear margin and long-term follow-up with an endoscope are necessary.