Adenomatous neuroendocrine tumors of the middle ear (MEANTs) with local invasion and lymph nodes metastasis: A brief report of a rare neoplasm.

Adenomatous neuroendocrine tumors of the middle ear (MEANTs) are very rare neoplasms which are composed of both epithelial and neuroendocrine components. They have mostly bland histology and indolent biological behavior, yet they may recur and metastasize. Here we present a case of MEANT with ipsilateral local brain, bone and nerve invasion and bilateral cervical lymphadenopathy in a 48 years old male with history of recurrent chronic otitis media and cholesteatoma. The patient underwent an initial fine-needle aspiration biopsy (FNAB) of an enlarged cervical lymph node followed by surgical excision of the tumor and immunohistochemistry which confirmed the diagnosis.