Медицинская библиотека · Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2007

Transoral laser microsurgery for untreated glottic carcinoma.

Grant David G, Salassa John R, Hinni Michael L, Pearson Bruce W, Hayden Richard E, Perry William C

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Аннотация

OBJECTIVES

To report the oncology and functional outcomes of transoral laser microsurgery (TLM) for untreated glottic carcinoma.

STUDY

DESIGN

A 2 center prospective case series analysis.

SETTING

Academic, tertiary referral centers.

RESULTS

Seventy-six patients underwent TLM. Pathologic T stages were: T1, 45 (59%); T2, 21 (28%); T3, 5 (7%); and T4, 5 (7%). Five (7%) patients had neck dissections. Five (7%) patients received adjuvant radiotherapy. Mean follow-up was 42 months. Respective T1 and T2 5-year Kaplan-Meier estimates were: local control, 90% and 93%; loco-regional control, 90% and 93%; disease specific survival, 90% and 93%; and overall survival, 94% and 93%. The average hospital stay was 2 days. Two (3%) patients experienced major complications. The overall laryngeal preservation rate was 95% (72 of 76).

CONCLUSIONS

TLM is a safe and effective treatment in select carcinoma of the glottic larynx. Low morbidity and mortality and short periods of hospitalization make TLM an attractive therapeutic option.

SIGNIFICANCE: TLM is an emerging strategy in the treatment of laryngeal cancer.

Для цитирования: Grant David G, Salassa John R, Hinni Michael L, Pearson Bruce W, Hayden Richard E, Perry William C. Transoral laser microsurgery for untreated glottic carcinoma.. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. 2007. DOI: 10.1016/j.otohns.2007.05.064.

Предметные рубрики MeSH

Adult Aged Aged, 80 and over Carcinoma, Squamous Cell Cohort Studies Databases, Factual Female Glottis Humans Laryngeal Neoplasms Laser Therapy Male Microsurgery Middle Aged Mouth Retrospective Studies Treatment Outcome

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