Head & neck · 2016
Hyperbaric oxygen therapy for maxillary bone radiation-induced injury: A 15-year single-center experience.
Оценочное исследованиеСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Gavriel Haim, Eviatar Ephraim, Abu Eta Rani
Аннотация
BACKGROUND: Although hyperbaric oxygen therapy (HBOT) is used to treat chronic radiation tissue injury, clinical evidence supporting its use in maxillary bone osteoradionecrosis (ORN) is lacking. Therefore, the purpose of this study was to report our results of collected patient outcomes from a single center's large experience using HBOT to treat maxillary bone ORN.
METHODS: From 1999 to 2015, 21 patients received treatment for maxillary bone ORN at our center. The medical records were retrospectively reviewed for the following variables: age, sex, comorbidities, tumor stage and site, previous surgery, previous radiotherapy or chemoradiation therapy, HBOT data, response to treatment and further management.
RESULTS: A positive clinical outcome from HBOT occurred in 85.7% of patients with ORN and was proven radiologically in 14 of 15 patients (93.3%). In 5 patients, reconstructive surgery was required thereafter.
CONCLUSION: Controversy exists regarding the management of ORN of the maxillofacial skeleton. Our large, single-center experience probably supports the efficacy of HBOT for maxillary bone ORN. © 2016 Wiley Periodicals, Inc. Head Neck 39: 275-278, 2017.
METHODS: From 1999 to 2015, 21 patients received treatment for maxillary bone ORN at our center. The medical records were retrospectively reviewed for the following variables: age, sex, comorbidities, tumor stage and site, previous surgery, previous radiotherapy or chemoradiation therapy, HBOT data, response to treatment and further management.
RESULTS: A positive clinical outcome from HBOT occurred in 85.7% of patients with ORN and was proven radiologically in 14 of 15 patients (93.3%). In 5 patients, reconstructive surgery was required thereafter.
CONCLUSION: Controversy exists regarding the management of ORN of the maxillofacial skeleton. Our large, single-center experience probably supports the efficacy of HBOT for maxillary bone ORN. © 2016 Wiley Periodicals, Inc. Head Neck 39: 275-278, 2017.
Предметные рубрики MeSH
AdultAgedCarcinoma, Squamous CellCohort StudiesDatabases, FactualFemaleFollow-Up StudiesHead and Neck NeoplasmsHumansHyperbaric OxygenationMagnetic Resonance ImagingMaleMaxillaMaxillary Sinus NeoplasmsMiddle AgedOsteoradionecrosisRadiation InjuriesRadiotherapyRetrospective StudiesRisk AssessmentSquamous Cell Carcinoma of Head and NeckTomography, X-Ray ComputedTreatment Outcome