Медицинская библиотека · Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2016

Prediction of outcome by lymph node ratio in patients with parotid gland cancer.

Meyer M F, Kreppel M, Meinrath J, Grünewald I, Stenner M, Drebber U, Quaas A, Odenthal M, Semrau R, Huebbers C U, Zöller J, Huettenbrink K-B, Buettner R, Beutner D

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Аннотация

OBJECTIVE

Lymph node ratio (LNR) has been shown to be an independent predictor of recurrence risk and survival in different entities of carcinoma.

METHODS

In this retrospective chart review, 128 patients with parotid gland cancer (PGC) subsequently treated by primary surgery were included. About 64% (n = 82) of these patients were additionally treated with adjuvant radiotherapy. Five-year overall survival rates were determined by subgroups based on LNR value.

RESULTS

Lymph node ratio was found to be significantly associated with overall survival rate (P < 0.001). Using univariate analyses, pathological tumour-node-metastasis (TNM)-stage, UICC-stage grouping and extracapsular spread were found to be significant predictors of overall survival (P < 0.001). However, with a multivariate analyses, LNR remained the only independent predictor of overall survival (P = 0.043).

CONCLUSIONS

After surgery for PGC, evaluation of the neck using LNR was found to reliably stratify the overall survival rate.

Для цитирования: Meyer M F, Kreppel M, Meinrath J, Grünewald I, Stenner M, Drebber U, Quaas A, Odenthal M, Semrau R, Huebbers C U, Zöller J, Huettenbrink K-B, Buettner R, Beutner D. Prediction of outcome by lymph node ratio in patients with parotid gland cancer.. Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery. 2016. DOI: 10.1111/coa.12672.

Предметные рубрики MeSH

Adolescent Adult Aged Aged, 80 and over Carcinoma Female Humans Lymph Node Excision Lymph Nodes Male Middle Aged Neoplasm Staging Parotid Neoplasms Predictive Value of Tests Retrospective Studies Survival Rate Young Adult

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