18F-FDG PET/CT imaging of extensive systemic sarcoidosis with epididymal involvement.

Sarcoidosis rarely involves the male reproductive tract. We present an unusual case of extensive systemic sarcoidosis with epididymal involvement. The ¹⁸F-FDG PET/CT demonstrated extensive foci of hypermetabolic activity involving multiple lymph nodes, liver, epididymides, muscles, and subcutaneous tissues. After immunosuppressive therapy, a follow-up PET scan showed almost complete disappearance of the FDG accumulation except for in the hilar lymph nodes.