Epidemiologic patterns of frontal and maxillary sinus cancer.

A significant disease in mortality rates for maxillary and frontal sinus cancer was found for older females, particularly in urban areas of New York State, over a 30-year period. A similar observation was made for males residing in rural areas. The decline in female rates might be related to the discontinued use of carcinogenic agents such as Thorotrast, whereas that in males might be related to changes in those industries associated with an increased risk for these cancer sites.