[Results of animal experiments following the use of a new material--biocement--for osteoplasty and fixation of alloimplants].

We report on results obtained with biocement (BC), a new material recently developed in our laboratory, in animal experiments dealing with osseous repair in the facial area. The organic matrix of BC corresponds to the Bowen formula. Anorganic filler substances comprise Ca5 (PO4)3OH, Bioceramic A2 (Battelle) and Bioglass Hench. We applied the new material to the following surgical interventions in monkeys or dogs: reconstruction of the anterior wall of the frontal sinus; covering of skull cap defect with or without a lesion of the dura mater; fixation of autologous bone transplants; bridging of defect in the mandible and the fixation of alloimplants under stress. The histological preparations of undecalcified bone were examined by light microscopy, in polarized light, with the help of scanning electron-microscope and the interface evaluation between implant and bone with energy dispersive X-ray analysis. Direct contact between BC and bone, and interdigitations between the two, as well as new bone formation were the rule. In addition, very few reactive changes were observed in cerebro-meningeal tissues neighboring BC. The latter did also not disturb the regeneration of ciliated epithelium in its vicinity.