European journal of ophthalmology · 2010
Cytomegalovirus retinitis associated with Good's syndrome.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Mateo-Montoya Aranzazu, Stanescu Dinu, Wolff Benjamin, Sahel José-Alain, Bonnel Sébastien
Аннотация
PURPOSE: To report a case of cytomegalovirus (CMV) retinitis associated with Good's syndrome.
METHODS: A 57-year-old man presented to our ophthalmology clinic with complaints of visual loss in the left eye for 2 weeks. His medical anamnesis revealed myasthenia gravis, thymoma resection, multiple chest infections, and Campylobacter septicemia. Left eye examination revealed mild anterior uveitis, moderate vitritis, and superotemporal active retinitis.
RESULTS: Polymerase chain reaction of both aqueous humor and vitreous tap were positive for CMV DNA, which suggested CMV retinitis. The patient was treated with systemic treatment of acyclovir and ganciclovir combined with weekly intravitreal injections of ganciclovir and foscarnet. Retinitis resolved within 3 weeks and visual acuity improved.
CONCLUSIONS: CMV retinitis can be associated with Good's syndrome.
METHODS: A 57-year-old man presented to our ophthalmology clinic with complaints of visual loss in the left eye for 2 weeks. His medical anamnesis revealed myasthenia gravis, thymoma resection, multiple chest infections, and Campylobacter septicemia. Left eye examination revealed mild anterior uveitis, moderate vitritis, and superotemporal active retinitis.
RESULTS: Polymerase chain reaction of both aqueous humor and vitreous tap were positive for CMV DNA, which suggested CMV retinitis. The patient was treated with systemic treatment of acyclovir and ganciclovir combined with weekly intravitreal injections of ganciclovir and foscarnet. Retinitis resolved within 3 weeks and visual acuity improved.
CONCLUSIONS: CMV retinitis can be associated with Good's syndrome.
Предметные рубрики MeSH
AcyclovirAgammaglobulinemiaAntiviral AgentsAqueous HumorCytomegalovirusCytomegalovirus RetinitisDNA, ViralDiagnosis, DifferentialDrug Therapy, CombinationFluorescein AngiographyFollow-Up StudiesFundus OculiGanciclovirHumansInjectionsMaleMiddle AgedPolymerase Chain ReactionSyndromeThymomaThymus NeoplasmsVisual AcuityVitreous Body