Study on the Pathogenic Mechanism of Pasteurella multocida.

Pasteurella multocida is highly prevalent in animal populations. It is usually a component of the normal microbiome of the oral, nasopharyngeal and upper respiratory tracts of animals and can cause varying degrees of infection and even death in animals. P. multocida poses a threat to public health safety because humans can be infected by being bitten by infected animals or coming into contact with their nasal secretions. This article summarises the morphological and culture characteristics of P. multocida, in addition to serotyping, virulence factors and pathogenesis, aiming to explore the mechanism by which the pathogen establishes acute and chronic infections. The article also summarises the mechanism underlying the activation of inflammasomes after P. multocida infection, providing a reference for exploring the epidemiological laws and pathogenesis of the bacterium and for formulating prevention and control strategies.