Ocular immunology and inflammation · 2009
Fluocinolone acetonide intravitreal implants in Vogt-Koyanagi-Harada disease.
Клинический случайСтатьяПоддержка NIH: внешняя программаПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Khalifa Yousuf, Loh Allison R, Acharya Nisha R
Аннотация
PURPOSE: To describe the use of fluocinolone acetonide implants (Retisert) in Vogt-Koyanagi-Harada disease (VKH).
DESIGN: Interventional case series.
METHODS: Retrospective review of medical records.
RESULTS: Two patients with VKH requiring high-dose systemic corticosteroid therapy to control their inflammation and bilateral serous retinal detachments received bilateral fluocinolone acetonide implants. Upon tapering of systemic corticosteroids, one patient had recurrent serous retinal detachments and the other patient's anterior chamber and vitreous inflammation returned.
CONCLUSIONS: The authors' experience with fluocinolone acetonide implants in VKH has been mixed with an inability to fully taper off of systemic corticosteroids.
DESIGN: Interventional case series.
METHODS: Retrospective review of medical records.
RESULTS: Two patients with VKH requiring high-dose systemic corticosteroid therapy to control their inflammation and bilateral serous retinal detachments received bilateral fluocinolone acetonide implants. Upon tapering of systemic corticosteroids, one patient had recurrent serous retinal detachments and the other patient's anterior chamber and vitreous inflammation returned.
CONCLUSIONS: The authors' experience with fluocinolone acetonide implants in VKH has been mixed with an inability to fully taper off of systemic corticosteroids.
Предметные рубрики MeSH
Administration, OralDose-Response Relationship, DrugDrug Administration ScheduleDrug ImplantsDrug Therapy, CombinationFemaleFluocinolone AcetonideGlucocorticoidsHumansInjections, IntravenousMalePrednisoneRecurrenceRetinal DetachmentRetrospective StudiesTreatment OutcomeUveomeningoencephalitic SyndromeVitreous BodyYoung Adult