Tumori · 2024
Is motherhood still possible after pelvic carbon ion radiotherapy? A promising combined fertility-preservation approach.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Barcellini Amelia, Cassani Chiara, Orlandi Ester, Nappi Rossella E, Broglia Federica, Delmonte Maria Paola, Molinelli Silvia, Vai Alessandro, Vitolo Viviana, Gronchi Alessandro, D'Ambrosio Gioacchino, Cobianchi Lorenzo, Fiore Maria Rosaria
Аннотация
INTRODUCTION: Preserving the endocrine and reproductive function in young female cancer patients undergoing pelvic radiation is a significant challenge. While the photon beam radiation's adverse effects on the uterus and ovaries are well established, the impact of pelvic carbon ion radiotherapy on women's reproductive function is largely unexplored. Strategies such as oocyte cryopreservation and ovarian transposition are commonly recommended for safeguarding future fertility.
METHODS: This study presents a pioneering case of successful pregnancy after carbon ion radiotherapy for locally advanced sacral chondrosarcoma.
RESULTS: A multidisciplinary approach facilitated the displacement of ovaries and uterus before carbon ion radiotherapy, resulting in the preservation of endocrine and reproductive function.
CONCLUSION: The patient achieved optimal oncological response and delivered a healthy infant following the completion of cancer treatment.
METHODS: This study presents a pioneering case of successful pregnancy after carbon ion radiotherapy for locally advanced sacral chondrosarcoma.
RESULTS: A multidisciplinary approach facilitated the displacement of ovaries and uterus before carbon ion radiotherapy, resulting in the preservation of endocrine and reproductive function.
CONCLUSION: The patient achieved optimal oncological response and delivered a healthy infant following the completion of cancer treatment.