Multifocal intraocular malignant melanoma: report of two cases and review of the literature.

PURPOSE: To describe two eyes from two patients with multifocal primary intraocular melanoma.

DESIGN

Two case reports.

METHODS

The history and histologic findings in the enucleated eyes of two patients with multifocal intraocular melanoma are described in comparison to previously reported cases.

MAIN OUTCOME MEASURES: Pathologic examination of enucleated eyes.

RESULTS

One of the two eyes contained mixed cell type melanomas, and one eye contained spindle cell type melanomas. Examination of serial sections showed no continuity between the intraocular melanomas. There were no associated ocular or systemic conditions with the multifocal intraocular melanomas.

CONCLUSIONS

Multifocal primary intraocular melanoma is rare. There is no known predisposing factor to this condition.