Annals of nutrition & metabolism · 2010
Passive smoke exposure and circulating carotenoids in the CARDIA study.
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Widome Rachel, Jacobs David R, Hozawa Atsushi, Sijtsma Femke, Gross Myron, Schreiner Pamela J, Iribarren Carlos
Аннотация
BACKGROUND/AIMS: Our objective was to assess associations between passive smoke exposure in various venues and serum carotenoid concentrations.
METHODS: CARDIA is an ongoing longitudinal study of the risk factors for subclinical and clinical cardiovascular disease. At baseline in 1985/1986, serum carotenoids were assayed and passive smoke exposure inside and outside of the home and diet were assessed by self-report. Our analytic sample consisted of 2,633 black and white non-smoking adults aged 18-30 years.
RESULTS: Greater total passive smoke exposure was associated with lower levels of the sum of the three provitamin A carotenoids, alpha-carotene, beta-carotene, and beta-cryptoxanthin (-0.048 nmol/l per hour of passive smoke exposure, p = 0.001), unassociated with lutein/zeaxanthin, and associated with higher levels of lycopene (0.027 nmol/l per hour of passive smoke exposure, p = 0.010) after adjustment for demographics, diet, lipid profile, and supplement use. Exposure in both home and non-home spaces was also associated with lower levels of the provitamin A carotenoid index.
CONCLUSION: Cross-sectionally, in 1985/86, passive smoke exposure in various venues was associated with reduced levels of provitamin A serum carotenoids.
METHODS: CARDIA is an ongoing longitudinal study of the risk factors for subclinical and clinical cardiovascular disease. At baseline in 1985/1986, serum carotenoids were assayed and passive smoke exposure inside and outside of the home and diet were assessed by self-report. Our analytic sample consisted of 2,633 black and white non-smoking adults aged 18-30 years.
RESULTS: Greater total passive smoke exposure was associated with lower levels of the sum of the three provitamin A carotenoids, alpha-carotene, beta-carotene, and beta-cryptoxanthin (-0.048 nmol/l per hour of passive smoke exposure, p = 0.001), unassociated with lutein/zeaxanthin, and associated with higher levels of lycopene (0.027 nmol/l per hour of passive smoke exposure, p = 0.010) after adjustment for demographics, diet, lipid profile, and supplement use. Exposure in both home and non-home spaces was also associated with lower levels of the provitamin A carotenoid index.
CONCLUSION: Cross-sectionally, in 1985/86, passive smoke exposure in various venues was associated with reduced levels of provitamin A serum carotenoids.
Предметные рубрики MeSH
AdolescentAdultAnalysis of VarianceBiomarkersBlack PeopleCarotenoidsChromatography, High Pressure LiquidCoronary Artery DiseaseCross-Sectional StudiesEducational StatusEnvironmental ExposureEnvironmental MonitoringEpidemiological MonitoringFemaleHumansLipidsLongitudinal StudiesLycopeneMaleRisk FactorsSex DistributionSmokingSurveys and QuestionnairesTobacco Smoke PollutionUnited StatesWhite PeopleYoung AdultBlack or African American