[Colorectal cancer: epidemiologic characteristics in a hospital center of Rosario, Argentina].

OBJECTIVE

To obtain clinical and epidemiological information that could be relevant for the purpose of screening and diagnostic strategies in colorectal cancer (CRC).

PATIENTS AND

METHODS

A retrospective, descriptive, observational study was performed during a three year-period at the Hospital Provincial del Centenario in Rosario, Argentina. A population of symptomatic patients referred for colonoscopic examination was evaluated after the histopathologic diagnosis of colorectal adenocarcinoma was made. A total of 1.543 colonoscopies was evaluated. Relevant information was retrieved from clinical records, and endoscopic, pathologic and tomography examinations.

RESULTS

Eighty six cases of CRC were diagnosed, with an incidence rate of CRC in the study population of 5.6%. Eighty six percent of patients were older than 50 years. Seventy five percent of tumors were located in the sigmoid colon and rectum. Synchronic lesions were found in 5.8% of tumor cases. Type 2 stenotic lesions were preferentially found in the left colon, whereas the site of most type 1 lesions was within the right colon. Most tumors (89.70%) were moderately well-differentiated adenocarcinomas. The most frequent site of metastases was the liver (64%).

CONCLUSIONS

In this population of symptomatic patients, 75% of colorectal tumors were found in the sigmoid colon and rectum, with 5.8% of cases showing a second, synchronous tumor. More than 80% of neoplastic lesions occurred in patients aged 50 or older and almost 90% were moderately well-differentiated adenocarcinomas. These data suggest guidelines for a proper strategy to prevent CRC.