Acta otorrinolaringologica espanola · 2002
[Early glottic carcinoma: a clinico-pathological study].
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Martín Villares C, Poch Broto J, Ortega Medina L, González Gimeno M J, Iglesias Moreno M C, Santos Corchero J M
Аннотация
UNLABELLED: The aim of the present study is to evaluate histopathological features of malignization of laryngeal dysplasia and recurrence of early glottic carcinoma.
PATIENTS AND METHODS: A prospective study was perform in a cohort of 134 patients who underwent surgery between 1992/99 at the ENT department of the Complutense University of Madrid. Tumor localization, malignization rate and recurrence rate were studied in 68 cases of laryngeal dysplasia, 11 of in situ-carcinoma and 55 of microinvasive carcinoma.
RESULTS: Nine laryngeal dysplasias experienced invasive carcinoma (13%) and six patients with invasive glottic carcinoma had laryngeal recurrence (11%), all of them with anterior commisure involvement. Eight patients underwent total laryngectomy for recurrence (6%) and three patients died of laryngeal cancer.
CONCLUSIONS: Anterior commisure involvement was the most important risk factor in early glottic carcinoma.
PATIENTS AND METHODS: A prospective study was perform in a cohort of 134 patients who underwent surgery between 1992/99 at the ENT department of the Complutense University of Madrid. Tumor localization, malignization rate and recurrence rate were studied in 68 cases of laryngeal dysplasia, 11 of in situ-carcinoma and 55 of microinvasive carcinoma.
RESULTS: Nine laryngeal dysplasias experienced invasive carcinoma (13%) and six patients with invasive glottic carcinoma had laryngeal recurrence (11%), all of them with anterior commisure involvement. Eight patients underwent total laryngectomy for recurrence (6%) and three patients died of laryngeal cancer.
CONCLUSIONS: Anterior commisure involvement was the most important risk factor in early glottic carcinoma.