Archives of surgery (Chicago, Ill. : 1960) · 2003
T1a breast carcinoma and the role of axillary dissection.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Schneidereit Nathan P, Davis Noelle, Mackinnon Murray, Speers Caroline H, Truong Pauline T, Olivotto Ivo A
Аннотация
HYPOTHESIS: Axillary dissection (AD) does not affect recurrence or survival in T1a breast cancer.
DESIGN: Cohort study comparing patients who underwent AD and those who did not.
SETTING: Provincial cancer agency.
PATIENTS: Six hundred ninety-one women with pathologically diagnosed T1a tumors.
MAIN OUTCOME MEASURES: Rates of axillary metastases stratified according to grade and lymphovascular and/or neural invasion, rates of relapse, and disease-specific survival.
RESULTS: Grade 1, 2, and 3 tumors without lymphovascular and/or neural invasion had axillary nodal involvement rates of 0.7%, 7%, and 7.8% of patients, respectively; with lymphovascular and/or neural invasion, axillary nodes were involved in 9.1%, 39.3%, and 44.4%, respectively. No statistically significant differences were found between the cohorts in relapse rates (P =.70) or survival (P =.84).
CONCLUSION: Higher tumor grade and lymphovascular and/or neural invasion increased the rate of nodal metastases in T1a tumors, but AD did not improve relapse rates or breast cancer-specific survival.
DESIGN: Cohort study comparing patients who underwent AD and those who did not.
SETTING: Provincial cancer agency.
PATIENTS: Six hundred ninety-one women with pathologically diagnosed T1a tumors.
MAIN OUTCOME MEASURES: Rates of axillary metastases stratified according to grade and lymphovascular and/or neural invasion, rates of relapse, and disease-specific survival.
RESULTS: Grade 1, 2, and 3 tumors without lymphovascular and/or neural invasion had axillary nodal involvement rates of 0.7%, 7%, and 7.8% of patients, respectively; with lymphovascular and/or neural invasion, axillary nodes were involved in 9.1%, 39.3%, and 44.4%, respectively. No statistically significant differences were found between the cohorts in relapse rates (P =.70) or survival (P =.84).
CONCLUSION: Higher tumor grade and lymphovascular and/or neural invasion increased the rate of nodal metastases in T1a tumors, but AD did not improve relapse rates or breast cancer-specific survival.